Pair 1: Gilbert’s disease (lack of lipase leading to jaundice or anemia), prostate cancer, glaucoma, Alzheimer’s disease.
Pair 2: Congenital tremor, colon cancer, learning disabilities, hearing impairment or color blindness.
Pair 3: Abnormal blood vessel growth, lung cancer, prostate cancer, primary tremor.
Pair 4: Huntington’s chorea, wrist deformity, cleft lip, prenatal teeth, Parkinson’s disease.
Pair 5: Cri-du-chat syndrome (small head, unusual facial features, cry like a cat), baldness and acne, premature aging syndrome, joint deformities.
Pair 6: Muscle coordination and cramps, diabetes, epilepsy.
Pair 7: Diabetes, physical and mental developmental disorders, cystic fibrosis, obesity.
Pair 8: Werner’s syndrome (premature aging syndrome occurring during puberty), Burkitt’s lymphoma.
Pair 9: Melanoma tumors, tuberous sclerosis, epilepsy, sebaceous gland tumors, intellectual disabilities.
Pair 10: Friedreich’s ataxia (muscle incoordination), cerebral atrophy (gradual loss of vision).
Pair 11: Premature coronary heart disease, diabetes, multiple endocrine neoplasia.
Pair 12: Currently undiscovered.
Pair 13: Breast cancer, retinoblastoma, Wilson’s disease (liver and nervous system disease), Patau syndrome (eye, brain, circulatory system defects, cleft palate).
Pair 14: Senile dementia (gradual loss of memory).
Pair 15: Prader-Willi syndrome (intellectual disability, obesity, short stature), Angelman syndrome (spontaneous laughter, spasmodic movements, other motor and cognitive impairments), Marfan syndrome (connective tissue lesions connecting organ system).
Pair 16: Familial Mediterranean fever, polycystic kidney disease (numerous cysts in the kidneys), intestinal dysfunction.
Pair 17: Tumor suppressor protein defects (susceptible to cancer, breast cancer).
Pair 18: Niemann-Pick disease (anemia, enlarged liver, spleen, lymph nodes, digestive and neurological defects, pancreatic cancer).
Pair 19: Atherosclerosis, intellectual disability, hair loss, cataracts.
Pair 20: Immunodeficiency.
Pair 21: Down syndrome, leukemia, Alzheimer’s disease, scleroderma.
Pair 22: Chronic myeloid leukemia (bone marrow replaced by malignant white blood cells leading to chronic myeloid leukemia).
Pair 23: X chromosome: Duchenne muscular dystrophy, Klinefelter syndrome (XXY males with small testes, infertility, female characteristics), Turner syndrome (XO females, underdeveloped secondary sexual characteristics, no puberty, short stature), hemophilia.