If the following conditions are present, it is recommended to cancel fresh embryo transfer and consider frozen embryo transfer after adjusting the body condition:
Poor Endometrial Conditions:
During the ovarian stimulation process, ultrasound indicates uneven endometrial echogenicity, and on the day of transfer, the endometrial thickness is <7mm or >15mm, there is intrauterine fluid accumulation, or conditions such as hydrosalpinx, intrauterine adhesions, endometrial polyps, endometriosis, or endometritis that affect endometrial receptivity, which are unfavorable for embryo implantation.
Ovarian Hyperstimulation Syndrome (OHSS):
When the number of eggs retrieved is ≥15, E2 levels are ≥5000pg/mL, accompanied by severe abdominal distention, pain, or ascites.
Inappropriate Hormone Levels:
Elevated levels of progesterone (P) (>1.5ng/mL) on the day of hCG injection, which may affect endometrial receptivity.
Use of Clomiphene or Luteal Phase Stimulation Protocol.
Unfit Physical Conditions for Transfer:
If severe systemic illnesses like a cold, fever, or significant urinary or reproductive tract infections occur during ovarian stimulation.
For factors such as hydrosalpinx, intrauterine adhesions, endometrial polyps, endometriosis, or endometritis that decrease endometrial receptivity, it is recommended to undergo active treatment first.
Treatment Recommendations for Specific Conditions:
- Hydrosalpinx: Tubal ligation or removal surgery; treat inflammation accordingly.
- Intrauterine Adhesions: Hysteroscopic adhesiolysis.
- Endometrial Polyps: Hysteroscopic polypectomy.
- Endometriosis: GnRH agonists (downregulation medications).
- Endometritis: Antibiotic treatment.
- Uneven Endometrial Echogenicity: Diagnostic hysteroscopy to identify the cause and provide targeted treatment.
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